The ASP process is capable of handling chemically diverse organic solvents and solvent mixtures with a wide variety of boiling points, however preferred solvents are acetone and methanol.

Applicability for solids is almost limitless as long as the drug(s) can be dissolved in a suitable solvent.

Further, polymers (water soluble and insoluble) and soluble excipients can be precipitated with the ASP process.